Bone marrow necrosis at transformation of chronic granulocytic leukaemia treated with interferon.

نویسندگان

  • J R Kendra
  • S Pickens
  • A K Singh
چکیده

A patient with chronic myeloid leukaemia was treated with interferon without using conventional cytotoxic agents. Bone marrow necrosis developed at the onset of blast transformation. It is suggested that cytotoxic drugs should be given before treatment with interferon for chronic myeloid leukaemia. Cytotoxic drugs may also be needed to prevent rapid bone marrow growth once interferon has been withdrawn.

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عنوان ژورنال:
  • Journal of clinical pathology

دوره 45 9  شماره 

صفحات  -

تاریخ انتشار 1992